3D illustration made from SEM imagery. This illustration depicts a three-dimensional (3D) computer-generated image of a fluconazole-resistant species from the genus of fungal organisms, Candida. In this particular view, you'll note that there are clusters, as well single blastoconidia, which are the asexually-produced reproductive cells that are produced through the process of budding, which are attached to the septate hyphal filaments. The artistic recreation was based upon scanning electron micrographic imagery. Some Candida strains are increasingly resistant to first-line and second-line antifungal treatment agents. Recent data demonstrate a marked shift among infections towards Candida species with increased resistance to antifungal drugs including azoles and echinocandins. CDC conducts multicenter surveillance for antifungal resistance in the United States, candidal infections, their economic impact, and possible areas where prevention and control strategies can be focused.