RNA INTERFERENCE. Interfering RNA RNAi _ stage 6. The RISC complex RNA_induced silencing complex is linked to a fragment of single_stranded RNA RNA guide, breaks away from the RNA target molecule that has just cleaved. It is then free to cleave another molecule of specific RNA. Interfering RNA is a mean for the cell to destroy the RNA parasites viruses RNA, transposons. The Dicer protein, a type III ribonuclease, fixes to the double_stranded RNA, and cleaves it into fragments of 21_25 nucleotide