Portuguese explorer Prince Henry, known as the Navigator, was the first European to methodically explore Africa and the oceanic route to the Indies. From his residence in the Algarve region of southern Portugal, he directed successive expeditions to circumnavigate Africa and reach India. In 1420, Henry sent an expedition to secure the uninhabited but strategic island of Madeira. In 1425, he tried to secure the Canary Islands as well, but these were already under firm Castilian control. In 1431, another Portuguese expedition reached and annexed the Azores.