Using recombinant DNA technology, a transgenic mouse has been engineered whose bone marrow is protected from the toxic effects of chemotherapy by expression of the MDR 1 gene. This 'animal system' allows rapid screening of drugs which inhibit the multidrug transporter and heralds a new era of using transgenic animals for pharmacologic screening. Multidrug resistance resulting from expression of an energy-dependent drug efflux pump encoded by the human MDR gene is a major impediment to effective | Stock Photo #4391-141

Stock Photo #4391-141, Using recombinant DNA technology, a transgenic mouse has been engineered whose bone marrow is protected from the toxic effects of chemotherapy by expression of the MDR 1 gene. This

Stock Photo - Using recombinant DNA technology, a transgenic mouse has been engineered whose bone marrow is protected from the toxic effects of chemotherapy by expression of the MDR 1 gene. This 'animal system' allows rapid screening of drugs which inhibit the multidrug transporter and heralds a new era of using transgenic animals for pharmacologic screening. Multidrug resistance resulting from expression of an energy-dependent drug efflux pump encoded by the human MDR gene is a major impediment to effective
Credit: National Cancer Institute / Science Faction / SuperStock
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4391-141
Contemporary
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Estimated Online Delivery: Immediate
High
12" x 8"
A4
300 dpi

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17.9" x 11.9"
A3
300 dpi

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